EC Accepts, published online ahead of print on 16 October 2009
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Eukaryotic Cell doi:10.1128/EC.00245-09
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Hwp1 and Related Adhesins Contribute to Both Mating and Biofilm Formation in Candida albicans

Iuliana V. Ene and Richard J. Bennett*

Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912

* To whom correspondence should be addressed. Email: Richard_Bennett{at}brown.edu.


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Abstract

Candida albicans Hwp1, Hwp2, and Rbt1 are related cell wall proteins expressed during the programs of sexual differentiation and filamentous growth. In this study, we compare strains lacking either single factors, or a combination of these genes, and demonstrate distinct but overlapping roles in mating and biofilm formation.






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